PARNet
Background
PARNet represents the European Pediatric Anesthesia research Network. All centers running pediatric anesthesia and interested in being part of large collaborative projects are welcome to be part of the network. For this reason multiple projects will be performed under the PARNet umbrella.
Chair
Prof. Nicola Disma, IRCCS Istituto Giannina Gaslini, Genova, Italy
Vice-Chair
Prof. Maren Kleine-Brueggeney, U German Heart Center Berlin and Charité – Universitaetsmedizin, Berlin, Germany
Steering committee members
Arash Afshari – Rigshospitalet, Denmark
Karin Becke – Cnopf Children’s Hospital, Germany
Nicola Clausen – University Hospital Odense, Denmark
Margaret Ekstein – Telaviv Hospital, Israel
Peter Frykholm – University of Uppsala, Sweden
Patricio González – La Paz Children’s Hospital, Spain
Walid Habre – University of Geneva, Switzerland
Thomas Riva -University of Bern, Switzerland
Carolina Romero – University Hospital, Spain
Francis Veyckemans – Hôpital Jeanne de Flandre, France
Britta von Ungern Sternberg – University of Western Australia, Australia
Vinicius Quintao – Universidade de São Paulo, Hospital das Clínicas, Faculdade de Medicina, Brazil
Anna Camporesi – Buzzi Children’s Hospital, Milan, Italy
Jean-Philippe Salaün – CHU Caen Normandie, Caen, France
Robert Frithiof – Uppsala University, Sweden
Jonny Kenth – Royal Manchester Children’s Hospital, Manchester, UK
Sonia Garcés-Sánchez – Hospital Universitari i Politècnic La Fe, Valencia (Spain)
Collaboration
ESAIC-ESPA-PARNet collaboration :
The PARNet Research Group is part of the ESAIC-ESPA collaboration which aims to bring together networks from both the societies in order to develop and run research projects.
espa
Ongoing Projects
CRICKET (Critical Events during tracheal intubation in kids)
A prospective observational study looking at major complications occurring during tracheal intubation in children undergoing general anaesthesia. Children from 0 to 16 years requiring tracheal intubation for general anaesthesia performed by the anaesthesia team are eligible for the study.
The aim is to include 100,000 patients within a period of 3 consecutive months, in 500 centres spread in all continents.
Status:
• 380 centres showed interest to participate from all continents
• Recruitment is ongoing
You can still register your interest to participate at: https://redcap.link/CRICKETstudy
For further information contact the study coordinator at: CRICKET@insel.ch
Explore the website at: www.cricketstudy.eu
Principal investigators: Prof. Nicola Disma and Prof. Thomas Riva
EUROFast (European Preoperative Fasting Audit)
A prospective observational study with the primary aim to determine the safety of reducing the required fasting time for clear fluids to at least one hour before elective procedures (as recommended in the ESAIC guideline). Secondary aims are to investigate risk factors for aspiration and real fasting times associated with registered events.
Study is completed:
• 31 centres participated
• 306900 anaesthetics included
For further information please contact: eurofast@uu.se
Principal investigators: Dr/Prof Peter Frykholm
New Proposals
The Big Apple Study
International observational study on the current practice of ventilation strategies in children undergoing general anaesthesia and the occurrence post-operative pulmonary complications. The study includes a 14-day inclusion period in each centre and is complemented by a pilot study taking place in the Amsterdam UMC. Currently 57 centres in 23 countries have included > 2.300 patients. Patients recruitment is finishing shortly.
For further information contact: bigapple@amsterdamumc.nl
Explore the website at: https://icuresearch.nl/studies/big-apple
Principal Investigator: Dr/Prof David van Meenen
PORPOISE Study
Focuses on planning physiological monitoring in the operating room and predicting outcomes using infra-red sensors. It is a feasibility study involving 500 children from 3-6 centers.
The ultimate aim is for this study to lead into a randomized controlled trial (RCT).
As of December 1st, 2025, the PORPOISE Feasibility study is running smoothly. Inclusion has started at all five sites (Perth, Sao Paolo, Brussels, Genova and Uppsala) and 250 out of the planned 500 patients have been enrolled so far.
Principal Investigator: Dr/Prof Peter Frykholm
POAKIDS (A European Multicentre Prospective Study of Postoperative Acute Kidney Injury in Hospitalized Paediatric Patients)
European multicentre prospective study focusing on postoperative acute AKI in children undergoing non-cardiac surgery. Secondary endpoint includes markers from urine.
The POAKIDS is in the final phase of preparation and will commence recruiting research subjects during 2026.
Principal Investigator: Prof. Robert Frithiof
SUSTAIN-EUROPE
The SUSTAIN-EUROPE Trial aims to describe the current anaesthesia practices in paediatric and adult patients undergoing surgery with anaesthesia care across Europe (including inhalational and intravenous general anaesthesia, regional anaesthesia, sedation, and combinations thereof) in a large-scale, prospective, observational study. By providing information on the status-quo we seek to identify potential areas for improvement of sustainable practices that can be addressed in future studies.
The study will be open for centres during one year. Data collection will be facilitated by a dedicated app and will last one week (= 5 consecutive days).For more information, please visit our website (https://esaic.org/sustainable-anaesthesia-practices-in-europe/) or contact us at sustain-europe@esaic.org