Open Sidebar

MOPED-MAD

Background

The European Society of Anaesthesiology and Intensive Care supports and facilitates meetings and communication between Research Groups.

The Management and Outcomes of the Perioperative Care of People with Diabetes (MOPED) and Metabolic Acquired Diseases (MAD) initiative was established to improve understanding of perioperative care and outcomes in patients with diabetes, obesity and metabolic diseases undergoing surgery.

The initial international MOPED prospective observational study¹ included over 6,000 surgical patients with diabetes, providing valuable insight into diabetes, perioperative glucose management and outcomes across multiple centres. This collaborative effort demonstrated the feasibility and value of large international datasets in identifying modifiable risk factors and informing evidence-based practice.

Building on this foundation, the research scope has expanded to include Metabolic Acquired Diseases (MAD), particularly obesity, which represents another major and growing challenge in perioperative medicine. Patients with metabolic disorders frequently present with complex comorbidities that influence surgical risk, recovery, and long-term outcomes. The MOPED-MAD research group aims to address these challenges through collaborative international research within the perioperative medicine community.

Objectives

The MOPED-MAD research group seeks to advance perioperative care through coordinated, high-quality and multinational collaborative clinical research. Key objectives include:

1. Improving perioperative diabetes management by investigating the relationship between preoperative glycaemic control (e.g., HbA1c), perioperative hyperglycaemia, and postoperative outcomes in large observational cohorts. And by developing personalised perioperative diabetes care strategies, including personalized glucose targets and evaluation of technologies such as continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII) systems in the surgical setting.
2. Investigating metabolic disorders such as obesity and their impact on surgical outcomes, including large prospective studies comparing outcomes between patients with normal BMI and those with severe obesity.

Mission

The mission of the MOPED-MAD research group is to improve perioperative outcomes for patients with diabetes and metabolic disorders through collaborative, data-driven research and guideline development.

The group aims to:

• Foster international collaboration between clinicians and researchers in perioperative medicine.
• Generate robust evidence to guide personalised perioperative management strategies.
• Translate research findings into clinical guidelines and practical tools for clinicians.
• Support multicentre research initiatives within the ESAIC research network and beyond.
• Ultimately improve patient safety, recovery, and long-term outcomes for surgical patients with metabolic diseases.

Through coordinated research, education, and guideline development, MOPED-MAD seeks to become a leading international platform for advancing perioperative care in this rapidly growing patient population.

^{1 Buggy DJ, Columb MO, Hermanides J, Hollmann MW, Coburn M, Zarbock A; MOPED Investigators. Management and Outcomes of Perioperative Care of People with Diabetes across Europe (MOPED): a prospective, observational study. Lancet Reg Health Eur. 2025 Nov 20;61:101535}

Contact Person : research@esaic.org